Tel Aviv University (TAU) researchers have developed an innovative closed-eye imaging technology designed to track clinical responses in individuals who are unresponsive but still breathing, such as those in sleep, under anesthesia, or in intensive care units.
Described in the journal Communications Medicine, this novel method leverages touchless infrared imaging to monitor changes in pupil size and gaze direction behind closed eyes. This advancement marks the first time such detailed monitoring is possible without direct contact.
The technology can detect a range of responses, including seizures, nightmares, the depth of sedation, and pain levels. It is particularly useful for assessing responsiveness and pain in patients who may have experienced trauma or are undergoing intensive care.
Pupil size, which naturally fluctuates to regulate light entering the eye, also dilates in response to stimuli like sudden events or pain. This dilation is part of the autonomic nervous system's alarm response, preparing the body for action.
The research team highlighted that their method successfully tracks the precise dynamics of the pupillary light reflex under closed-eye conditions. It reveals changes in pupil size after each light flash in individual subjects and accurately estimates eye gaze direction.
Backed by a patent application, the researchers believe this technology paves the way for developing devices with wide-ranging clinical and commercial applications, potentially transforming patient care and monitoring practices worldwide.
Reference(s):
Researchers develop new tech to track responses in sleep, anesthesia
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