In a significant advancement for medical science, researchers from the Chinese mainland have developed a novel biodegradable composite material designed to accelerate wound healing and promote the growth of skin-like tissue.
The collaborative study between the Zhongnan Hospital of Wuhan University and the Wuhan University of Technology has been published in the International Journal of Biological Macromolecules.
This innovative biocomposite is crafted from silk fibroin, sodium alginate, and other natural polymers. Its unique micro-nano layered structure guides skin cells to migrate and integrate into various skin layers, facilitating full-thickness skin repair and regeneration, explained Wang Xinyu, a professor at the Wuhan University of Technology.
Unlike artificial skin substitutes, the resulting tissue closely resembles native skin and maintains essential sensory functions such as touch and pain perception.
The material is fully absorbable by the human body, breaking down into harmless byproducts like amino acids, carbon dioxide, and water. This feature eliminates the need for removal and reduces the risk of complications.
Applications of this breakthrough extend to repairing skin and mucosal defects in the oral and maxillofacial regions, as well as addressing burn-induced skin injuries. Additionally, it offers a sustainable solution to the shortage of autologous skin graft materials and mitigates issues related to non-degradable repair materials and allergic reactions.
Reference(s):
Researchers develop biodegradable material for enhanced wound healing
cgtn.com
