In a groundbreaking advancement, researchers from Peking University have developed the world’s first high-density, 1,024-channel neural probe, marking a significant leap in neuroscience technology.
Led by Duan Xiaojie, the research team designed the innovative probe, named Neuroscroll, which can isolate single neuronal activities from 1,024 densely spaced channels. This flexibility allows the probe to be tuned from 1 cm to 10 cm in length, making it adaptable for studying brain sizes ranging from rodents to primates.
During their experiments, the team successfully monitored the activities of over 700 single neurons across the entire depth of a macaque monkey's brain simultaneously. Additionally, the Neuroscroll demonstrated exceptional biocompatibility by maintaining stable neural recordings in rat brains for up to two years.
This remarkable achievement not only highlights the probe’s long-term stability but also its potential to revolutionize brain research by providing more detailed and comprehensive data on neuronal activities. The findings were published online on Monday in the prestigious journal Nature Neuroscience.
The development of Neuroscroll opens new avenues for understanding complex brain functions and could pave the way for advancements in treating neurological disorders, enhancing brain-machine interfaces, and expanding our overall knowledge of the brain's intricate networks.
Reference(s):
China develops first neural probe to record activity in macaque brain
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