Early Insulin Therapy Reduces Stroke and Heart Failure Risks in Type 2 Diabetes

In a groundbreaking study, Chinese scientists have demonstrated the effectiveness of early insulin therapy for newly diagnosed patients with type 2 diabetes (T2D). The therapy significantly cuts the risks of stroke and hospitalization due to heart failure compared to patients who did not receive the treatment.

A joint research team led by Professor Weng Jianping from Anhui Medical University, alongside scientists from the University of Science and Technology of China, Southern Medical University, and Peking University, conducted a 24-year observational study involving 5,424 T2D patients across the country.

The findings revealed that patients who underwent early insulin therapy experienced a 31 percent reduced risk of stroke and a 28 percent lower risk of hospitalization due to heart failure. Additionally, the therapy improved biomarkers related to low-grade inflammation and endothelial function, which are key indicators of cardiovascular risk.

This comprehensive study provides compelling evidence supporting the adoption of early insulin therapy as a first-line treatment option for newly diagnosed type 2 diabetes patients. The research was published in the international journal of Signal Transduction and Targeted Therapy in early June.

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