In a groundbreaking advancement for medical science, Chinese researchers have successfully transplanted a gene-edited pig kidney into a brain-dead individual, with the organ functioning perfectly for nine days. This achievement follows last month's successful transplant of a gene-edited pig liver.
The procedure, guided by Dou Kefeng of the Chinese Academy of Sciences and performed by Qin Weijun and his team at Xijing Hospital in Xi'an, Shaanxi Province, took over six hours. The team carefully inserted the genetically modified kidney into the patient’s right iliac fossa. Post-operation assessments revealed excellent blood perfusion and immediate urine production, indicating no signs of hyperacute rejection.
Qin emphasized that the surgical plan underwent rigorous review and approval by multiple academic and ethics committees, adhering strictly to national regulations. The patient's family consented to the research, supporting its contribution to medical progress.
With advancements in gene editing and immunology, xenotransplantation research in China has made significant strides. Qin highlighted that this milestone offers promising solutions to the global organ shortage crisis and paves the way for new treatments for end-stage renal disease in the future.
Earlier this year, the same hospital successfully transplanted a gene-edited pig liver into a brain-dead patient, which functioned for ten days before the study concluded based on the family's wishes. These pioneering efforts signify critical steps forward in the field of xenotransplantation.
Reference(s):
Chinese researchers transplant gene-edited pig kidney into human body
cgtn.com
